Novel Gene Implicated in PH Development in Preclinical Study

Novel Gene Implicated in PH Development in Preclinical Study

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Novel Gene Implicated in PH Development in Preclinical Study

A gene called DNMT3B was found for the first time to be a mediator of blood vessel wall growth, and has been implicated in the development of pulmonary hypertension (PH) in a rat study. This gene, which regulates inflammatory pathways by epigenetic mechanisms, may be a potential therapeutic target for the treatment of PH, scientists said.  The study, “DNA methyltransferase 3B deficiency unveils a new pathological mechanism of pulmonary hypertension,” was published in the journal Science…

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