Cancer Therapy Seen to Protect Blood-brain Barrier, Ease MS in Mouse Model

Cancer Therapy Seen to Protect Blood-brain Barrier, Ease MS in Mouse Model

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Cancer Therapy Seen to Protect Blood-brain Barrier, Ease MS in Mouse Model

Imatinib, a cancer treatment, stopped an injury response mechanism of the central nervous system (CNS) from activating, damage to which is a hallmark of multiple sclerosis (MS), an early study reported. Treatment with imatinib lessened immune cell infiltration and eased disease progression in mouse models of MS. Study researchers suggested that treatments with a similar mechanism of action might be of benefit in neurological diseases marked by BBB disruption. The study “Blocking PDGF-CC signaling ameliorates…

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