Blood Neurofilament Light Chain Levels May Be Myelopathy Biomarker in ALD

Blood Neurofilament Light Chain Levels May Be Myelopathy Biomarker in ALD

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Blood Neurofilament Light Chain Levels May Be Myelopathy Biomarker in ALD

Elevated blood levels of a nerve cell-derived component known as neurofilament light chain (NfL) could be a potential biomarker for myelopathy — spinal cord degeneration — in patients with adrenoleukodystrophy (ALD), a study suggests. The study, “Plasma NfL and GFAP as biomarkers of spinal cord degeneration in adrenoleukodystrophy,” was published in the journal Annals of Clinical and Translational Neurology. All men with ALD, and about 80% of women with the genetic brain disorder, develop progressive myelopathy,…

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