NfL Levels in Blood Vesicles May Mirror Severity of Motor Symptoms

NfL Levels in Blood Vesicles May Mirror Severity of Motor Symptoms

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NfL Levels in Blood Vesicles May Mirror Severity of Motor Symptoms

Higher levels of neurofilament light chain (NfL) — a biomarker of nerve cell damage — inside small vesicles in the blood associate with more severe motor symptoms, particularly slow movement and rigidity, in people with Parkinson’s disease, a small study suggests. However, no significant changes in NfL levels inside these vesicles, called exosomes, were observed between Parkinson’s patients and healthy individuals. Future studies analyzing these levels in a larger group of patients and over time…

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