Boosting Cholesterol Recycling in Brain Facilitates Myelin Repair, Study Says

Boosting Cholesterol Recycling in Brain Facilitates Myelin Repair, Study Says

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Boosting Cholesterol Recycling in Brain Facilitates Myelin Repair, Study Says

New research in mice suggests that poor recycling of cholesterol in the brain impairs the repair of myelin, the protective coat surrounding nerve cells that is lost in multiple sclerosis (MS). Pharmacological stimulation of cholesterol synthesis by brain immune cells — called microglia — boosted the regeneration of myelin, supporting its potential as a new therapeutic strategy for MS. The study, “Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis,” was published in the…

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